Market Outlook:

The anticipated global total ankle replacement systems market size is poised to reach USD XX. XX Million by 2024, with a projected escalation to USD XX.XX Million by 2032, reflecting a compound annual growth rate (CAGR) of X.X% during the forecast period.

Total ankle replacement also known as total ankle arthroplasty, it is a surgical procedure to relieve pain and regain the function by replacing the ankle joint with an implant. It is often considered for patients with severe arthritis or joint damage that has not responded to treatment. The damaged ankle joint will be removed & replaced with artificial implant which is made of plastic and metal to restore the function to the joint during the surgery. The main objective of ankle replacement system is to provide pain relief while preserving ankle motion, hence the patient has less pain and better function during activity.

The growth of the market has been affected by the increasing cases of osteoarthritis and rheumatoid arthritis. This increase is due to factors such as aging, genetic predispositions, and changes in lifestyle choices. In 2019, According to data published by the World Health Organization (WHO) approximately 18 million people worldwide suffered from rheumatoid arthritis. As a result, people’s pain requires preservation or restoration of joint function which are projected to increase the need for joint replacement instead of fusion or repair. Furthermore, advancements in technology are one of the major driving factors in this market. Newer implants have been built to have improved material compositions, such as cobalt-chromium alloys and titanium, that offer greater durability and bio-compatibility. The evolving surgical techniques with minimal invasion and robotic and computer-assisted navigation systems are increasing the accuracy of surgery and recovery times. Modular implants that promote more customization and better anatomical fit are increasingly in favour among surgeons and patients.

While the market shows potential, the high costs of surgery and possible complications, such as infection or implant failure, are two principal challenges to bringing the procedure to more users. However, innovation and strategic developments, including acquisitions and new product launches, by key players such as Stryker, Zimmer Biomet, and Smith+Nephew, are likely to be drivers for further growth and to overcome the challenges involved.

Market Dynamics:

Driver:

Factors such as aging population, increasing orthopedic diseases and injuries, increasing popularity of minimally invasive surgery, and technological advancements in ankle replacement equipment are increased the business growth during the forecast period.

The people with osteoporosis are increasing year on year, which helps for the growth of the market. For example, according to data released by the Bone Health and Osteoporosis Foundation (BHOF) in May 2023, osteoporosis is one of the leading causes of bone fractures in the United States, affecting approximately 10 million Americans and approximately 44 million in the United States. Therefore, the burden of bone loss can lead to ankle fractures in the general population, which may require ankle surgery and is therefore expected to drive market growth during the forecast period.

Orthopedic conditions such as arthritis, osteoarthritis, and rheumatoid arthritis due to age-related bone deterioration make it difficult to stay healthy. For example, according to an article published in Open Science in January 2023, ankle sprains are the most common injury among adults, and as people age, this is an injury that is expected to more than double each year, creating a global medical burden by 2050. In addition, according to data published by the World Health Organization in October 2022, an estimated 1.4 billion people worldwide are expected to be 60 years of age or older in 2030, compared to 1 billion years ago and further this is expected to reach approximately 2.1 billion in 2050.

Restraint:

The paramount risk of infections linked to total ankle arthroplasty is restraining the growth of the Total Ankle Replacement Market. A postoperative infection, especially deep about the implant site, can be associated with severe complications such as prolonged hospital stay, additional surgery, and even removal or replacement of implants. All these risks augment healthcare expenditure but also decrease the confidence of patients to undergo such procedures. Infections, often resulting from medical illness such as diabetes or immunocompromised state, have a major impact on outcome and success rate. Therefore, alternative treatment options, such as ankle fusion, which greatly reduces mobility but has a much smaller risk of infection, become appropriate alternative.

Opportunity:

The rising advancement in technologies provide lucrative opportunities for the market growth. Osteoporosis and osteoarthritis are a global health concern, especially among the elderly. As hips, knees, ankles, and shoulders are replaced more frequently, the number of specialized centers offering joint replacements is also increasing. Furthermore, thanks to advanced technology and biomechanical advancements in ankle arthroplasty over the last 20 years, modular stem implants have demonstrated exceptional longevity and success. Moreover, it also provides entrepreneurs with business strategies such as partnerships and product development to grow their businesses.  In 2021 November, Stryker company has launched Infinity Resection Guide for the use of joint replacements. The Infinity Resection Guide allows surgeons to perform fewer surgeries during total joint replacement compared to the Lord’s Needle procedure. It uses only one guide for drilling and cutting, helping to improve orthopedic surgery operation and reduce the number of steps in patient surgical preparation.

Additionally, during 2022 in April, Medline UNITE Foot & Ankle developed an implant Calcaneal Fracture Plating System and IM Fibula, enabling surgeons in the United States to treat various types of fractures, surgeries, and body replacements from a bowl. This release offers, a titanium foot and ankle trauma system for almost all fractures requiring ORIF repair using plates and screws fixation. Hence, the growing advanced technologies and new product launches by key players will increase the total ankle replacement system market during the forecast period.

Key Players:

• Allegra
• CONMED Corporation
• Corin Group
• Exactech, Inc.
• Integra LifeSciences
• restor3d
• Smith+Nephew
• Stryker Corporation
• Wright Medical Group N.V.
• Zimmer Biomet
• Small Bone Innovation, Inc
• KYOCERA Medical Corporation
• Biomet Inc.
• Tornier
• DePuy Synthes
• Others

Recent Development:

• During 2021 November, The Infinity Resection Guide for Ankle Replacement Surgery simplifies the procedure by eliminating surgery complexities This advancement represents a major advancement in Stryker surgical technology, providing surgeons with a more efficient operation.
• In July 2020, Vilex, company has acquired DT MedTech, LLC, including the Hintermann family for total ankle replacement. DT MedTech manages manufacturing according to its quality process and ships worldwide. Vilex supports Hintermann extensively in the U.S. using its sales force to provide additional service and support which is creating lucrative opportunity to grow the company revenue.
• In 2021 January, DJO, LLC company has acquired Trilliant Surgical, a company developing foot and ankle orthopedic implant products. This acquision venture advances product differentiation and effective treatments for total ankle replacement market.
• In 2021, Smith and Nephew announced new products for outdoor equipment at the American Academy of Orthopaedic Surgeons 2021 Annual Meeting. The product, CADENCE total ankle planar dome system and the ATLASplan shoulder 3D planning and patient-specific instrumentation (PSI) system to address total ankle and total shoulder replacement issues.

Based on the type of fixation, the global total ankle replacement market is segmented into cemented type, cement less type, and hybrid type. Among these, the cement segment is expected to account for the largest share of the global total joint replacement market during the forecast period. This is because many sports injuries are caused by poor lifestyle, inadequate rest and rehabilitation, and increased fitness and participation in sports. Another factor is the acceptance and understanding of minor surgery. Cemented implants are highly beneficial for patients with reduced bone stock as in osteoporosis and heavy joint arthritic changes, in which one may not achieve the required primary stability using other fixation options like cement less implants. The use of bone cement to increase the bond between the implant and the bone minimizes the chances of loosening of the implants and, consequently, improves long-term stability and durability.

Advances in cement formulations and implant designs have strengthened this market. Modern bone cements with improved biocompatibility and mechanical properties reduce the chances of failure of any implant or infection, and therefore improve outcomes for patients.

Based on end use, the total ankle replacement system market is segmented into hospitals, orthopedic hospitals, and other end users. The hospital segment is expected to generated revenues of xx USD million by 2023. Facility data, analytics data, and recorded results can influence the hospital’s purchasing decisions and implant selection to provide quality and satisfactory patient care. Hospitals with an Orthopedic and Orthopedic Department can receive referrals from primary care physicians or other healthcare providers for patients requiring total ankle replacement system surgery. The increasing number of cases has increased the demand for total ankle replacement implants in these hospitals.

The increasing prevalence of arthritis, traumatic injuries, and other degenerative joint conditions is enhancing the patient inflow to the hospital. Furthermore, they are typically referral centers for complicated cases; this adds to their share in the market. Moreover, continuous developments in implant technology and minimally invasive surgical techniques are increasingly being implemented in the hospitals, boosting their status as the dominant end-use segment in total ankle replacement.

North America region has holding the highest growth rate among other regions and is expected to grow total ankle replacement market by 2032. Due to the desire to maintain mobility and quality of life, patients in this region may seek total ankle replacement surgery as an alternative to ankle surgery or treatment. In addition, large population in North America is affected by arthritis and degenerative diseases, increasing the need for TAR surgery. For example, according to data from the Centers for Disease Control and Prevention (CDC) National Health Interview Survey (NHIS), approximately 53 million people in the United States live with some type of arthritis as rheumatoid arthritis, etc. the estimation was done during 2019 to 2021. As the aged population rising and obesity increasing, the incidence of disease called arthritis are expected to increase, hence the increasing the need for surgical procedures such as total ankle replacement systems also increases in accordance with the same in the future.

• Two-component fixed bearing
• Three-component mobile bearing

• Cemented
• Cement-less
• Hybrid

• Hospitals
• Orthopedic clinics
• Other end-users

• HINTEGRA total ankle replacement
• Scandinavian total ankle replacement
• Salto total ankle replacement
• BOX total ankle replacement
• INBONE total ankle replacement
• Zenith total ankle replacement
• Others

North America

• USA
• Canada
• Mexico

Europe

• France
• UK
• Spain
• Germany
• Italy
• Rest of Europe

Asia Pacific

• China
• Japan
• India
• South Korea
• Rest of Asia Pacific

Middle East & Africa

• GCC
• South Africa
• Rest of the Middle East & Africa

• Brazil
• Argentina
• Rest of South America

What to Expect from Industry Profile?

1. Save time carrying out entry-level research by identifying the size, growth, major segments, and leading players in the Total Ankle Replacement Systems market in the world.
2. Use PORTER’s Five Forces analysis to determine the competitive intensity and therefore market attractiveness of the Global Total Ankle Replacement Systems market.
3. Leading company profiles reveal details of key Total Ankle Replacement Systems market players’ global operations, strategies, financial performance & recent developments.
4. Add weight to presentations and pitches by understanding the future growth prospects of the Global Total Ankle Replacement Systems market with forecast for the decade by both market share (%) & revenue (USD Million).

• The Global Total Ankle Replacement Systems Market is poised to grow at a CAGR of XX% from 2025 to 2032.

• The North America region is expected to create more opportunities in the market.

• Allegra, CONMED Corporation, Corin Group, Exactech, Inc., Integra LifeSciences, restor3d, Smith+Nephew, Stryker Corporation, Wright Medical Group N.V., Zimmer Biomet, Small Bone Innovation, KYOCERA Medical Corporation, Biomet, Tornier, DePuy Synthes, Others.

• By Product Type, By Fixation Type, By End-use, and By Design are the industry key segments considered for research study.

• The estimated revenue for the Global Total Ankle Replacement Systems Market in 2032 is USD XX Million.